Oncology · CAR-T cellular immunotherapy
CAR-T therapy in China,
at one-third the cost.
4 NMPA-approved products. Class A hospital cellular therapy programs. Real-world response rates matching US registration trials. All-in pricing $60–140k vs $400k+ in the US.
Approved products
Four NMPA-approved CAR-T products.
Yikaida 奕凯达
Axicabtagene ciloleucel (Yescarta licensed via Fosun Kite). DLBCL, follicular, mantle cell. The most internationally recognised brand in China.
All-in: $120–140k
Carteyva 倍诺达
Relmacabtagene autoleucel (JW Therapeutics). Comparable efficacy to Yescarta in head-to-head Chinese RWE data, ~30% lower price.
All-in: $80–110k
Fukerui 福可苏
Equecabtagene autoleucel (IASO Bio). BCMA-targeted CAR-T for r/r multiple myeloma. ~70% ORR in registration trial.
All-in: $100–130k
Yuanruida 源瑞达
Zevorcabtagene autoleucel (CARsgen). Second-generation BCMA CAR-T. Approved 2023 with strong response data.
All-in: $90–120k
Source: NMPA approval registry, manufacturer disclosures, Chinese RWE publications 2023–2024.
FAQ
CAR-T, in plain language.
- Is CAR-T therapy available in China for foreign patients?
- Yes. China has 4 NMPA-approved CAR-T products as of 2024 covering relapsed/refractory B-cell lymphomas, acute lymphoblastic leukaemia (ALL), and multiple myeloma. Treatment is delivered at Class A hospitals with NMPA-licensed cellular therapy laboratories. Total all-in cost runs $60,000–$140,000 — roughly one-third of US pricing.
- What CAR-T products are approved in China?
- Four NMPA-approved products: (1) Yikaida 奕凯达 (axicabtagene ciloleucel — Yescarta licensed via Fosun Kite); (2) Carteyva 倍诺达 (relmacabtagene autoleucel — JW Therapeutics, China-developed); (3) Fukerui 福可苏 (equecabtagene autoleucel — IASO Bio); (4) Yuanruida 源瑞达 (zevorcabtagene autoleucel — multiple myeloma indication, CARsgen). Indications and dosing differ — your oncologist will recommend based on disease and prior treatment lines.
- What conditions does CAR-T treat?
- Currently approved indications in China: relapsed/refractory diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, mantle cell lymphoma, B-cell ALL (acute lymphoblastic leukaemia), and relapsed/refractory multiple myeloma. Solid tumour CAR-T programs are in trials but not yet approved. CAR-T is a third- or fourth-line treatment after standard chemotherapy has failed.
- What are the response rates?
- Published Chinese real-world data closely match US registration trial data: ~80% overall response rate and ~50–55% complete response in DLBCL; ~90% in pediatric/young adult B-ALL; ~70–80% in multiple myeloma. Long-term remission (3+ years) occurs in ~40% of DLBCL responders. Outcomes depend on disease bulk, prior treatment lines, and toxicity management.
- How does CAR-T treatment work logistically?
- Six steps: (1) eligibility assessment + bridging chemotherapy if needed; (2) leukapheresis (~4 hours) to collect T-cells; (3) cells shipped to manufacturing facility; (4) genetic engineering and expansion (10–14 days); (5) lymphodepleting chemotherapy 3–5 days before infusion; (6) CAR-T infusion + 2–4 week inpatient observation for cytokine release syndrome (CRS) and neurotoxicity. Total stay: ~6 weeks.
- How much does CAR-T cost in China vs the US?
- China all-in cost (drug + hospitalisation + bridging therapy + 4 weeks observation): $60,000–$140,000 depending on product and centre. US list prices: Yescarta $373,000, Kymriah $475,000, Carvykti $465,000 — plus $100,000+ hospitalisation. China pricing reflects domestic manufacturing, lower facility costs, and competitive multi-product market.
- What hospitals offer CAR-T in China?
- Class A centres with NMPA-licensed cellular therapy facilities: Beijing 301 Hospital (PLA General Hospital), Renji Hospital Shanghai, Ruijin Hospital Shanghai, Peking Union Medical College Hospital, Tianjin Cancer Hospital, Sun Yat-sen University Cancer Center Guangzhou. Each centre has its own product partnerships — your case is assigned based on disease and product compatibility.
Eligibility check
in 7 business days.
Submit pathology, prior treatment history, and current imaging. A senior haematology-oncologist will confirm CAR-T candidacy and recommend product and centre.